In the summer of 1665, Cambridge University closed its gates and sent its students home to die or survive as fortune allowed. The plague had returned to England, as it had returned for three centuries, receding to the margins before flowering again in the bodies of the poor and then, inevitably, everyone else. The colleges emptied. The libraries locked. A 22 year-old with an undistinguished academic record rode back to his mother's farm in Lincolnshire and, with nothing else to do, began to think.

What Isaac Newton accomplished over the next eighteen months at Woolsthorpe Manor remains one of the most concentrated bursts of intellectual achievement in human history. He developed the foundations of calculus. He laid the groundwork for the laws of motion. He discovered that white light was composed of colours, then proved it with a prism and a darkened room. He began the calculations that would become the theory of universal gravitation. He did this in a farmhouse, in a plague year, in almost complete isolation, with no laboratory worth the name and no one to talk to but his mother and the occasional apple tree. When Cambridge reopened and he returned, he mentioned none of it for years. He had simply been passing the time.

The standard telling of this story treats Newton as an anomaly, the freakish productivity of a singular genius who happened to be stuck indoors. But Newton was not working in any vacuum. He was working in a very particular kind of intellectual vacuum, one that had been created by more than a century of violent upheaval in everything Europeans thought they knew. The plague that sent him home was only the most immediate manifestation of a deeper disruption. The old order was dying, and had been dying since Henry VIII broke with Rome. Newton, whether he knew it or not, was building something new in its ruins.

The Black Death had first arrived in England in 1348, killing perhaps half the population within two years. It never truly left. Every generation learned to listen for the bells, to read the bills of mortality, to understand that the boundary between the living and the dead was thinner than anyone preferred to acknowledge. By the time Elizabeth took the throne in 1558, plague was not history but habit, a recurring feature of English life as predictable as winter and considerably less survivable. The theatres closed when the sickness came; they reopened when it receded. Shakespeare's company knew this rhythm intimately. So did everyone else.

But the plague was only the most visceral of the disruptions. England had been Catholic, then Protestant, then Catholic again, then Protestant again, each reversal accompanied by executions, expropriations, and the sudden transformation of yesterday's martyrs into today's heretics. The monasteries had been dissolved; their libraries scattered or burned. The old learning, which had been preserved and transmitted by the Church for a thousand years, was suddenly suspect, not because it was wrong but because the people who had taught it had been revealed as fallible, political, capable of error and corruption. If the Church had been wrong about salvation, the central question of human existence, what else had it been wrong about? To be an educated person in 1590 was to know that your parents had believed things that could now get you killed, and that your children might believe things that would have gotten your parents killed. The ground was not stable. The certainties that had organised European life for a thousand years had cracked and, in places, collapsed entirely.

Into this atmosphere came the printing press, which had been invented more than a century earlier but was only now reaching the kind of saturation we would recognise as mass media. Suddenly, pamphlets could spread ideas faster than authorities could suppress them. Luther's theses had travelled across Europe in weeks; now every reformer and conspiracist, every genuine visionary and opportunistic fraud, could get their thoughts into circulation. The result was not enlightenment but cacophony. The Church said one thing; the reformers said another; the reformers disagreed violently among themselves. Everyone had a book to prove their case. The old gatekeepers could not keep the gates.

John Donne was born into this chaos in 1572, and he made the chaos itself into a kind of fuel. His family was Catholic in a Protestant country; his brother died in prison for harbouring a priest. Donne converted, or half-converted, or strategically converted. Scholars still argue about what he believed, and perhaps he did too. What is certain is that he wanted everything: the flesh and the spirit, the scandal and the sermon. He wrote love poetry that made readers blush and devotional poetry that cracked them open with longing for God, sometimes in adjacent lines. He married for love and destroyed his career in a single afternoon. He spent years in poverty, fathered twelve children, watched several of them die, then reinvented himself as a clergyman and became the most celebrated preacher in England. He strove, as one of his biographers observed, for both chaos and glory. He was, in this sense, perfectly suited to his age.

His poems are difficult because the world had become difficult. He yoked together things that should not fit: lovers and compasses, souls and drops of dew, the sacred and the profane. The famous conceits were not decorative. They were load-bearing, holding meaning together when everything else was coming apart. “The new philosophy calls all in doubt,” he wrote in 1611. The sun had been the centre of the universe; now it appeared the earth went around the sun. The heavens had been immutable; Galileo's telescope revealed spots on the sun and mountains on the moon. The old maps were wrong. The old manuscripts were corrupt. The authorities had been copying each other's mistakes for centuries. “'Tis all in pieces, all coherence gone,” Donne wrote, “all just supply, and all relation.” The world had fragmented. Donne's response was to build structures of meaning that could hold the pieces together by sheer force of syntax and metaphor, generating a new coherence where the old had failed. It was one way forward. Others would find different paths through the wreckage. Years later, ill with fever while the plague raged through London, Donne would write the words that have outlasted almost everything else he made, “never send to know for whom the bell tolls; it tolls for thee”. It was not despair. It was a statement of fact. In a city where the bells rang constantly for the dead, the question was not whether they tolled for you but when.

Shakespeare, Donne's elder by eight years, dramatised the same vertigo on a public stage. He put kings before audiences and showed them murdering their way to power, losing their grip on sanity, dying confused and alone. He gave us Hamlet, who cannot determine what is true or what action truth demands, who is paralysed not by cowardice but by the collapse of the frameworks that once made decisions possible. He gave us Macbeth, who mistakes prophecy for certainty and brings ruin on himself and everyone he loves. He gave us Lear, who cannot tell love from flattery and is stripped of everything by the difference. The plays do not tell you what to think. They test what can be thought. They weigh crowns against skulls, and the skulls do not reply. The audiences who watched, packed into the Globe on afternoons when the plague bills were low enough to permit performance, understood this was not abstraction. The uncertainty was theirs. Like Donne, Shakespeare offered no programme, no method, no way out. Only the most ferocious attention to what it felt like to be alive when the old certainties had cracked and nothing had yet risen to replace them.

Neither Donne nor Shakespeare offered systematic solutions. They were diagnosticians of crisis, not engineers of resolution. That work fell to Francis Bacon, born in 1561, who looked at the same collapse and saw not tragedy but opportunity. If the old ways of knowing had failed, you needed new ways of knowing. If the authorities had been wrong, you could not simply find better authorities. You needed methods that did not depend on authority at all, methods that could be checked and verified and repeated by anyone willing to do the work. He called this the Novum Organum, and it was essentially a manual for not getting fooled: observe carefully, experiment repeatedly, trust nothing that cannot be demonstrated, build knowledge from the ground up rather than deducing it from first principles that might themselves be mistaken.

Bacon was suspicious of language, of the tricks that rhetoric played on the mind, of the human tendency to find patterns where none existed and to believe things because they were elegantly expressed. He wanted a method that could survive the death of institutions, that would work even when no one agreed on first principles, even when the experts had been discredited, even when the very concept of expertise was under assault. Bacon himself got many things wrong; he underestimated mathematics, believed some empirically false claims, and never became a practicing experimentalist in the modern sense. But the method outlived his errors, which was precisely the point. The scientific method emerged not from the perfection of its architects but from the wreckage of confidence, from the discovery that everything previously known might be wrong. It was what remained when custom fell away.

This is the inheritance Newton carried with him to Woolsthorpe. He had been educated at a Cambridge still nominally teaching Aristotle, but Aristotle's physics was already dying, killed by Galileo's observations and Kepler's mathematics and the simple fact that the old models did not predict what the telescopes actually showed. The tools Bacon had described were lying around waiting to be used. The old order had been cleared away. What Newton found, in his solitude, was the order waiting underneath.

The famous apple, if it ever fell, was not a cause but a catalyst. Newton had been thinking about motion and force, about why the planets stayed in their orbits and why objects fell to earth. The mathematics of the time could not describe these phenomena adequately; he needed better mathematics, so he invented calculus. He needed to understand light in order to build better instruments, so he decomposed it into its spectrum and explained refraction. Each problem led to another, and he had nothing but time, no distractions, no teaching duties, no social obligations, just the quiet of a farmhouse and the pressure of a mind that could not stop working. Under that pressure, thought grew sharp and spare.

The laws he discovered were not inventions. They had always been there, governing the fall of apples and the orbits of planets, waiting for someone with the right tools and the right circumstances to find them. What was new was the method that could find them, the willingness to observe and calculate and test rather than defer to authorities who had been guessing all along. From the crisis came clarity. From the collapse of the old coherence came a new coherence, more durable because it did not depend on anyone's say-so, because it could be checked by anyone with sufficient patience and skill. Newton would later become President of the Royal Society, jealously guard his priority, engage in bitter disputes, and wield institutional power as ruthlessly as any courtier. The solitary genius became an authority himself. But the method did not require his permission to continue working. That was its strength.

Four centuries later, the texture feels familiar. The ground is shifting again. We too have experienced a communications revolution that has overwhelmed our institutions' capacity to manage information. The printing press took a century to destabilise European epistemology; social media has accomplished something comparable in two decades. We too have watched expertise lose its purchase, sometimes through genuine failure and sometimes through manufactured doubt. We too are swimming in a flood of text, uncertain which voices to trust, aware that the old filters have broken down but unable to agree on new ones.

The pandemic that began in 2020 made the parallel suddenly vivid. The theatres closed, as they had closed for Shakespeare's company. The universities sent students home, as Cambridge had sent Newton home. And the epistemic chaos that had been building for years became impossible to ignore. The case fatality ratio, the mechanisms of transmission, the efficacy of interventions were mapped in real time, revised in real time, contested in real time. Scientists, doing what scientists are supposed to do, changed their recommendations as evidence accumulated. Much of the public, longing for certainty, saw only confusion. The methods were working; the communication of those methods was not. We were watching, in compressed form, exactly what Bacon had warned about: the gap between how knowledge is actually built and how people want knowledge to feel.

The optimistic reading of the Elizabethan crisis is that it eventually produced the Enlightenment, the scientific revolution, the modern world. This is true, but “eventually” is doing considerable work in that sentence. Between the crisis of the sixteenth century and the stability of the eighteenth came the wars of religion, witch trials on an industrial scale, and devastation across the continent. The printing press enabled Luther, but it also enabled a century of pamphlet wars, conspiracy theories, and violent sectarian conflict. The old institutions could not contain the new information environment, and the result was chaos until new institutions slowly, painfully, emerged.

We are still in the chaos. We have not yet built the methods, the institutions, the habits of mind that can function in an environment of information overabundance. The arrival of artificial intelligence does not resolve this crisis; it industrialises it. The printing press broke the monopoly on who could speak; AI breaks the link between expression and the person expressing. We are uncertain not merely which human voices to trust but whether the voice is human at all, whether the image is real, whether the text was written by someone who believes it or generated by a system that believes nothing. The cost of producing convincing falsehood has collapsed. The epistemological questions that haunted Donne and Bacon have returned with new urgency. What can be known? How can it be verified? What holds when the old authorities fail?

Yet the work of building new methods has already begun, even if it does not yet have the coherence of a movement. Scientists are developing reproducibility standards, preregistration protocols, open data requirements that make verification possible without requiring trust in individual researchers. Engineers are building interpretability tools to understand what machine learning systems actually do, rather than accepting their outputs on faith. Journalists are experimenting with transparency about sourcing and correction. These are not solutions; they are the early scaffolding of solutions, the Baconian fumbling toward methods that might survive the current collapse. Most will fail. Some will not. That is how it works.

Those who lived through this crisis, and the Jacobean decades that followed, produced Shakespeare and Donne, the King James Bible, the essays of Bacon, the explorations that mapped coastlines no European had seen. They also produced the microscope, the telescope, William Harvey's discovery that blood circulates through the body, the first newspapers, the first stock exchange, and the logarithms that would make modern computing possible. It was not a time of paralysis but of ferocious creativity, precisely because the old forms had broken down and new ones had to be invented. When the authorities could not tell you what to think, you had to work it out for yourself. When the institutions could not be trusted to transmit knowledge, you had to develop methods that did not depend on institutions. The collapse was real, and the suffering was real, but the clearing of the ground made room for things that could not have grown in the old forest's shade.

Something similar is stirring now, for those with eyes to see it. The old media is dying, but new forms are being born in garages and bedrooms, just as the first newspapers emerged from coffeehouses and print shops. The university is creaking under pressures it was not designed to withstand, but knowledge is being created and transmitted in ways that would have been impossible a generation ago, reaching people who would never have had access to it. Most of what emerges will be forgotten. That was true in the seventeenth century too. What matters is that the work is being done.

Newton, in his farmhouse, did not know he was founding modern physics. He was simply trying to understand why things fell and how light worked. The institutions that would eventually house and transmit his discoveries did not yet exist, or existed only in embryonic form. He was working in the gap between one world and another, after the old one had collapsed and before the new one had taken shape. That gap is uncomfortable. It is also where new things come from.

The plague ended. Cambridge reopened. Newton returned, and the revolution he had started in isolation slowly, over decades, became the foundation of how we understand the physical world. The laws he discovered had always been there, governing the motion of bodies and the behaviour of light, waiting to be found. What was new was the method that could find them, the patient accumulation of observation and calculation that did not require anyone's permission or approval. From crowded graves came systems overthrown. And in the clearing that death and doubt had made, Newton found the order waiting there.

We cannot know what order waits in our own chaos. We are too close to it, too caught in the vertigo of transition. But the order is there, as it was there for the Elizabethans: not the old arrangement restored, which is never what happens, but something new, something that could not have emerged without the prior dissolution. The task is not to recover what has been lost but to build what comes next, using whatever tools we can fashion and whatever methods prove reliable. The ground is shaking. The authorities are faltering. The noise is deafening. This is not the end of knowing. It is, if we are fortunate and sufficiently diligent, the beginning of knowing differently.

The bells are still tolling. They always are. Donne was right about that: they toll for all of us, binding us together in vulnerability and mortality and the shared work of making sense of a world that does not explain itself. The libraries remain open. The questions keep being asked. Somewhere, in a bedroom, library, or garage, someone is thinking thoughts that will not be understood for years, building foundations for a world not yet imagined, working in solitude because the institutions cannot yet accommodate what they are doing. This is how it happens. This is how it has always happened. The old certainties fall. The plague clears the field. And in the silence that follows, if you listen carefully, you can hear the first scratching of a pen, the first tapping of keys, the patient work of discovering what holds.